This manual covers 5 pest and 5 disease constraints affecting coffee. These were identified and prioritized by participants at a Coffee Research Network (CORNET) Regional Coffee Stakeholders’ Workshop held in Nairobi in October 2004. For each, the manual provides a description to help with constraint diagnosis and identification of the causal organism. Information is provided on their importance (e.g. economic importance, coffee types affected), geographic occurrence, biology, and ecology (including survival, spread and life cycle of the causal organism) and on known approaches to management. These are supported by photographic illustrations principally of the organisms and the symptoms they induce on coffee. Detailed descriptions of the morphology of the relevant fungal and insect organisms is also provided, although this is intended more for the benefit of those who already have some knowledge and experience of these aspects and who also have access to microscopes and other equipment required to observe the organisms in detail. The manual has been produced in a user-friendly format, principally to meet the needs of service providers, including agricultural extension. However, it may also be suitable for direct consultation from some farmers.